Some reflections on talc poudrage

Some reflections on talc poudrage.

We read with interest the well researched article of Stefani et al. [1] about the different techniques of intrapleural talc. This technical paper really filled the gap in our knowledge following established evidences of superiority of the talc itself [2,3] over other products. We have a question and two comments. Could we be provided with data on the size of the talc particles? This intriguing ...

Pleurodesis, pH, and thoracoscopic talc poudrage.

Single center experience on talc poudrage morbidity: focus on high talc dosage

Malignant pleural effusion (MPE) is a common clinical problem of concern for most of the pneumologists and thoracic surgeons. A general consensus regarding the use of talc poudrage in treatment of MPE exists, but only few studies analyzed in detail talc insufflation related pulmonary morbidity. In particular, ARDS talc-related is caused by physical and chemical effects of the small talc particl...

Complications of talc poudrage in the United States.

A recent article in CHEST (June 2010) by Gonzalez et al 1 on the complications of talc pleurodesis is important because it may be the largest report on the use of Sclerosol talc (Bryan Corporation; Woburn, Massachusetts), the only proprietary talc sanctioned by the US Food and Drug Administration (FDA). The article would have been enhanced if the authors had shared their 1to 6-month success rat...

Phase III intergroup study of talc poudrage vs talc slurry sclerosis for malignant pleural effusion.

STUDY OBJECTIVE To demonstrate the efficacy, safety, and appropriate mode of instillation of talc for sclerosis in treatment of malignant pleural effusions (MPEs). DESIGN A prospective, randomized trial was designed to compare thoracoscopy with talc insufflation (TTI) to thoracostomy and talc slurry (TS) for patients with documented MPE. MEASUREMENTS The primary end point was 30-day freedom...